Hypoxia-inducible factor-2α (HIF-2α) is a key regulator of cellular adaptation to hypoxia, but its role in osteoarthritis (OA) remains incompletely defined. This study aimed to investigate the contribution of HIF-2α to OA pathogenesis and the underlying molec… For the full story, visit the source.
Science
HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis
Hypoxia-inducible factor-2α (HIF-2α) is a key regulator of cellular adaptation to hypoxia, but its role in osteoarthritis (OA) remains incompletely defined. This study aimed to investigate the contribution of HIF-2α to OA pathogenesis and the underlying molec…
By Pinpin Jiang, Hang Wang, Yujia Li, Yuanyu Zhang, Jingrui Huang, Yukun Xu, Dahai Rong, Danni Ruan, Yao Wang, Jie Yuan, Pengcui Li· Plos.org· 4 months ago· 2 min read
This summary is sourced from Plos.org. Read the full article at:Plos.org