The allosteric mechanisms by which lipid binding controls protein activity remain poorly understood. Here, the authors identify a lipid-triggered allosteric site in LC3 that remodels its receptor-binding interface upon membrane interaction. This site can be e… For the full story, visit the source.
Technology
A programmable lipid-triggered allosteric site modulates LC3 LIR receptor binding activity
The allosteric mechanisms by which lipid binding controls protein activity remain poorly understood. Here, the authors identify a lipid-triggered allosteric site in LC3 that remodels its receptor-binding interface upon membrane interaction. This site can be e…
By Deepanshi Gahlot, Jesu Castin, Shruti Mathur, Debajyoti Das, Ajit Kumar, Akanksha Arun, Chandrima Gain, Mridul Sharma, Ravi Kant Pal, Niyati Jain, Bichitra K. B· Nature.com· 1 day ago· 2 min read
This summary is sourced from Nature.com. Read the full article at:Nature.com